William Slayton, MD - Research

Research at a glance

Top areas of exploration

Hematopoietic Stem Cells , 12 publications
Bone Marrow Transplantation , 10 publications
Bone Marrow Cells , 9 publications
Hematopoietic Stem Cell Transplantation , 8 publications

Research activity

86 publications

2,301 citations

Why is this important?

Active clinical trials

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in P

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common鈥�

Investigators: Brian Stover, William Slayton
Status: Accepting Candidates
Ages: 2 Years - 25 Years
Sexes: All

A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment o

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after鈥�

Investigators: Brian Stover, William Slayton
Status: Accepting Candidates
Ages: N/A - 22 Years
Sexes: All

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma (RADICAL)

The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin鈥�

Investigator: William Slayton
Status: Accepting Candidates
Ages: 3 Years - 39 Years
Sexes: All

My publications

86 publications

2009

MLL/AF-4 leukemic cells recruit new blood vessels but do not incorporate into capillaries in culture or in a NOD/SCID xenograft model.

Leukemia

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2009

Post-Transplant Lymphoproliferative Disorder in Children: Recent Clinical Characteristics, Outcomes and Response To Dual Rituximab/Chemotherapy Combination

American Journal of Transplantation

2009

Post-Transplant Lymphoproliferative Disorder in Children: Recent Clinical Characteristics, Outcomes and Response To Dual Rituximab/Chemotherapy Combination

American Journal of Transplantation

2008

Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular niche following lethal irradiation.

Experimental hematology

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2008

Optimization of recombinant adeno-associated viral vectors for human beta-globin gene transfer and transgene expression.

Human gene therapy

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