William Slayton, MD - Research

Research at a glance

Top areas of exploration

Hematopoietic Stem Cells , 12 publications
Bone Marrow Transplantation , 10 publications
Bone Marrow Cells , 9 publications
Hematopoietic Stem Cell Transplantation , 8 publications

Research activity

86 publications

2,301 citations

Why is this important?

Active clinical trials

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refrac

This phase II trial tests the safety and best dose of revumenib in combination with chemotherapy, and evaluates whether this treatment improves the outcome in infants and young children who have leukemia that has come back (relapsed) or does not鈥�

Investigators: Brian Stover, William Slayton
Status: Accepting Candidates
Ages: 1 Month - 6 Years
Sexes: All

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open鈥�

Investigators: Brian Stover, William Slayton
Status: Accepting Candidates
Ages: N/A - 50 Years
Sexes: All

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other鈥�

Investigators: Brian Stover, William Slayton
Status: Accepting Candidates
Ages: 3 Years - 29 Years
Sexes: All

My publications

86 publications

2008

Philadelphia Chromosome Negative (Ph-) Very High Risk (Vhr) Acute Lymphoblastic Leukemia (All) in Children and Adolescents: the Impact of Intensified Chemotherapy On Early Event Free Survival (Efs) in Children'S Oncology Group (Cog) Study Aall0031

Blood

2008

Recombinant self-complementary adeno-associated virus serotype vector-mediated hematopoietic stem cell transduction and lineage-restricted, long-term transgene expression in a murine serial bone marrow transplantation model.

Human gene therapy

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2008

Stable integration of recombinant adeno-associated virus vector genomes after transduction of murine hematopoietic stem cells.

Human gene therapy

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2008

Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow.

Journal of pediatric hematology/oncology

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2007

Sites and kinetics of donor thrombopoiesis following transplantation of whole bone marrow and progenitor subsets.

Experimental hematology

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