- Investigator
- Nikolaus McFarland
- Status
- Accepting Candidates
Research at a glance
Top areas of exploration
- Parkinson Disease , 43 publications
- Supranuclear Palsy, Progressive , 18 publications
- Multiple System Atrophy , 14 publications
- Parkinsonian Disorders , 13 publications
Research activity
Focus
Dr. McFarland is a member of the Norman Fixel Institute for Neurological Diseases and the Center for Translational Research in Neurodegenerative Disease (CTRND), which aims to bring the bench research closer to the bedside. His research focuses on understanding the pathological mechanisms of Parkinson disease and related disorders, and on identifying novel biomarkers for early detection and tracking of disease and therapeutic development. A primary goal of his research is to identify and to develop potential novel therapeutics for Parkinson disease and related disorders. His research extends also to the clinic where he is actively involved in multiple clinical trials for atypical Parkinson disorders and Huntington disease.
Active clinical trials
This is a Phase 3, open-label study to evaluate the long-term safety and tolerability of valbenazine, and to provide participants continued access to valbenazine for the treatment of chorea associated with Huntington disease.
- Investigator
- Nikolaus McFarland
- Status
- Accepting Candidates
- Ages
- 18 Years - 75 Years
- Sexes
- All
The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease…
- Investigator
- Nikolaus McFarland
- Status
- Accepting Candidates
- Ages
- 30 Years - N/A
- Sexes
- All
My publications
Filter publications
97 publications
2020
Magnetic Resonance Imaging and Neurofilament Light in the Differentiation of Parkinsonism.
Movement disorders : official journal of the Movement Disorder Society
•2020
Mild cognitive impairment and dementia in motor manifest Huntington's disease: Classification and prevalence.
Journal of the neurological sciences
•2019
A turn for the worse: Turning performance in Parkinson's disease and Essential tremor.
Clinical biomechanics (Bristol, Avon)
•2019
Development and Validation of the Automated Imaging Differentiation in Parkinsonism (AID-P): A Multi-Site Machine Learning Study.
The Lancet. Digital health
•2019
Development of a transcallosal tractography template and its application to dementia.
NeuroImage
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