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Michael J Haller, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Michael J Haller

Research at a glance

Top areas of exploration

  • Diabetes Mellitus, Type 1 , 65 publications
  • Insulin , 15 publications
  • Blood Glucose , 14 publications
  • Glycated Hemoglobin , 13 publications

Research activity

145 publications

3,743 citations

Why is this important?

Focus

Dr. Haller's research focuses on predicting, preventing, and ultimately reversing type 1 diabetes through his participation in numerous clinical trials utilizing immunotherapies. Dr. Haller serves as the Principal Investigator for the University of Florida TrialNet Clinical Center, Chair of the TEDDY Clinical Implementation Committee, and PI of the UF/Stanford ECHO Collaborative. Dr. Haller also leads and participates in technology studies seeking to improve the lives of people living with diabetes through the use of pumps, continuous glucose monitors, and systems that automate insulin delivery.

Active clinical trials

FABULINUS

This is a randomized, parallel group, double-blind Phase 2 study with a 52-week blinded extension evaluating the safety and efficacy of 3 dose levels of frexalimab in comparison with placebo in participants with newly diagnosed T1D on insulin…

Investigator
Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
TN-31 JAKPOT T1D

A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
Protocol TN-25

The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to…

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
8 Years - 45 Years
Sexes
All

My publications

145 publications

2023

Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial

Diabetes Care

2023

Blue Circle ÍøºìºÚÁÏ: A Novel Patient-Centered Model of ÍøºìºÚÁÏ Care Delivery for Low-Income Patients With Type 1 Diabetes.

Journal of diabetes science and technology

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2023

CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study

Diabetes Care

2023

Disease progression joint model predicts time to type 1 diabetes onset: Optimizing future type 1 diabetes prevention studies.

CPT: pharmacometrics & systems pharmacology

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2023

Human immune phenotyping reveals accelerated aging in type 1 diabetes

JCI Insight