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Michael J Haller, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Michael J Haller

Research at a glance

Top areas of exploration

  • Diabetes Mellitus, Type 1 , 65 publications
  • Insulin , 15 publications
  • Blood Glucose , 14 publications
  • Glycated Hemoglobin , 13 publications

Research activity

145 publications

3,743 citations

Why is this important?

Focus

Dr. Haller's research focuses on predicting, preventing, and ultimately reversing type 1 diabetes through his participation in numerous clinical trials utilizing immunotherapies. Dr. Haller serves as the Principal Investigator for the University of Florida TrialNet Clinical Center, Chair of the TEDDY Clinical Implementation Committee, and PI of the UF/Stanford ECHO Collaborative. Dr. Haller also leads and participates in technology studies seeking to improve the lives of people living with diabetes through the use of pumps, continuous glucose monitors, and systems that automate insulin delivery.

Active clinical trials

FABULINUS

This is a randomized, parallel group, double-blind Phase 2 study with a 52-week blinded extension evaluating the safety and efficacy of 3 dose levels of frexalimab in comparison with placebo in participants with newly diagnosed T1D on insulin鈥

Investigator
Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
TN-31 JAKPOT T1D

A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
Protocol TN-25

The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to鈥

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
8 Years - 45 Years
Sexes
All

My publications

145 publications

2024

Multisite Quality Improvement Program Within the Project ECHO Diabetes Remote Network

The Joint Commission Journal on Quality and Patient Safety

2024

Not all healthcare inequities in diabetes are equal: a comparison of two medically underserved cohorts

BMJ Open Diabetes Research & Care

2024

One-Year Thermostability of Commercial Glargine and Human Insulin

Diabetes Care

2024

Serum exocrine pancreas enzymes are biomarkers of immunotherapy response in new-onset type 1 diabetes.

Frontiers in endocrinology

2024

Type 1 diabetes prevention clinical trial simulator: Case reports of model鈥恑nformed drug development tool

CPT: Pharmacometrics & Systems Pharmacology