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The Sponsor is developing KB408, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector engineered to deliver functional full-length human SERPINA1 to the airways of people with alpha-1 antitrypsin deficiency…

Investigator

Jorge E Lascano

Status

Accepting Candidates

Ages

18 Years - 70 Years

Sexes

All

This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.

Investigator

Jorge E Lascano

Status

Accepting Candidates

Ages

18 Years - N/A

Sexes

All

Phase 2 open label extension study to evaluate SAR447537 (INBRX-101) in adults with AATD emphysema

Investigator

Jorge E Lascano

Status

Accepting Candidates

Ages

18 Years - 80 Years

Sexes

All