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Jorge E Lascano, MD

Critical Care Specialist

Photo of Jorge E Lascano

Research at a glance

Top areas of exploration

  • alpha 1-Antitrypsin Deficiency , 9 publications
  • Pulmonary Disease, Chronic Obstructive , 8 publications
  • alpha 1-Antitrypsin , 7 publications
  • Cystic Fibrosis , 3 publications

Research activity

44 publications

427 citations

Why is this important?

Active clinical trials

Serpentine-1

The Sponsor is developing KB408, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector engineered to deliver functional full-length human SERPINA1 to the airways of people with alpha-1 antitrypsin deficiency…

Investigator
Jorge E Lascano
Status
Accepting Candidates
Ages
18 Years - 70 Years
Sexes
All
KB407-02

This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.

Investigator
Jorge E Lascano
Status
Accepting Candidates
Ages
18 Years - N/A
Sexes
All
ELEVAATE OLE

Phase 2 open label extension study to evaluate SAR447537 (INBRX-101) in adults with AATD emphysema

Investigator
Jorge E Lascano
Status
Accepting Candidates
Ages
18 Years - 80 Years
Sexes
All

My publications

44 publications

2023

Therapeutic drug monitoring in cystic fibrosis and associations with pulmonary exacerbations and lung function

Respiratory Medicine

2022

Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.

Respiratory research

•

2022

Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.

PloS one

•

2022

Evaluation of Clinical Predictors for Major Outcomes in Patients Hospitalized With COVID-19: The Potential Role of the Rothman Index.

Cureus

•

2022

Labelling Alpha-1 antitrypsin deficiency in the medical record - A call to action.

Respiratory medicine

•