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GAINESVILLE, Fla. 鈥� Researchers are one step closer to developing a simple, at-home test to prevent cervical cancer or treat it early, a new from and Purdue University researchers has found.

鈥淥ur results pave the way for us to develop inexpensive, fast and accurate preliminary screening tests for cervical cancer,鈥� said , D.V.M., Ph.D., the study鈥檚 senior author. 鈥淭his test has the potential to transform early-stage cervical cancer diagnosis and treatment, particularly in areas with limited access to health care.鈥�

Cervical cancer is the world鈥檚 fourth most common cancer in women. When it鈥檚 found early, it鈥檚 one of the most preventable and treatable cancers. The main screening method is an in-person Pap smear. The FDA the first at-home self-collection device, which screens for HPV, the virus that causes nearly all cervical cancers.

Still, these methods can be expensive, time-consuming and not always available. A new method based on measuring cellular proteins could reduce the need for expensive laboratory equipment and training.

In the new National Cancer Institute-funded study, researchers validated four proteins that were more abundant in swabs from women with high-grade precancerous lesions and tissue samples from patients.

They found the proteins could be used as sensitive and specific biomarkers to indicate precancerous lesions and to distinguish subtypes of cervical cancer. Precancerous lesions can usually be successfully treated, preventing cancer from developing. Knowing the subtype tells health care providers how aggressive or fast-moving the cancer is, helping them develop a treatment plan.

Next, the researchers plan to develop a standardized way to collect and process cervical cancer samples, paving the way for a point-of-care test. Point-of-care tests are portable tests that can be done in more convenient settings than a traditional medical laboratory, and they鈥檙e usually faster.

鈥淭his test would provide an affordable and scalable solution for improving cervical cancer prevention throughout the world,鈥� said Mohammed, co-leader of the 网红黑料 Cancer Center鈥檚 research program.

The study was of the June edition of the journal Cancers. Mohammed, a professor in the UF College of Veterinary Medicine鈥檚 small animal clinical sciences department, collaborated with researchers at Purdue University, where she worked before last year.