网红黑料

GAINESVILLE, Fla. 鈥� Higher fluoride levels in pregnant women are linked to increased odds of their children exhibiting neurobehavioral problems at age 3, according to a new study led by a University of Florida College of Public 网红黑料 and 网红黑料 Professions researcher.

The , based on an analysis involving 229 mother-child pairs living in a U.S. community with typical fluoride exposure levels for pregnant women in fluoridated regions in North America, appear May 20 in the journal JAMA Network Open. It is believed to be the first U.S.-based study to examine associations of prenatal fluoride exposure with parent-reported child neurobehavioral issues, which include symptoms of anxiety, difficulty regulating emotions and other complaints, such as stomachaches and headaches.

Fluoride, a mineral, has been added to community water supplies since the 1940s as a way to reduce dental cavities in children and adults. Nearly three-quarters of the U.S. population receives fluoridated tap water from community water systems. The impacts of fluoride on human health, both positive and negative, have been the subject of much recent debate and ongoing scientific scrutiny.

The study鈥檚 lead investigator , an assistant professor in the in the and , said that taken with other recent studies conducted in Canada and Mexico on the effects of fluoride on young children鈥檚 IQ, the findings suggest fluoride may negatively affect fetal brain development.

鈥淭here is no known benefit of fluoride consumption to the developing fetus,鈥� Malin said, 鈥渂ut we do know that there is possibly a risk to their developing brain. We found that each 0.68 milligram per liter increase in fluoride levels in the pregnant women鈥檚 urine was associated with nearly double the odds of children scoring in the clinical or borderline clinical range for neurobehavioral problems at age 3, based on their mother鈥檚 reporting.鈥�

The fluoride levels found in the study participants鈥� samples are typical for people living in communities with fluoridated water, the researchers say. However, according to the paper, authors do not know whether findings observed in this study are generalizable to other U.S. populations or are nationally representative and therefore more research is required to address that question.

Individual differences in a person鈥檚 fluoride exposure can be attributed to variances in dietary consumption, such as drinking and cooking with tap water versus filtered water, or consuming food and drinks naturally high in fluoride, including green and black tea, certain seafoods and foods sprayed with fluoride-containing pesticides.

For the new study, investigators used data from the Maternal and Developmental Risks from Environmental and Social Stressors, or MADRES, study conducted at the . MADRES is led by the senior author of the current fluoride study and an associate professor of clinical population and public health sciences, and a professor of population and public health sciences. The MADRES study follows a group of predominantly Hispanic women with low-income and their children living in Los Angeles County from pregnancy through childhood.

Researchers collected urine samples from MADRES participants during their third trimester of pregnancy. Urinary fluoride is the most widely used measure of individual fluoride exposure in epidemiological studies, including those assessing effects on fetal brain development. Because fluoride, when combined with disinfecting agents, may cause lead to leach from lead-bearing water pipes, the scientists conducted various analyses to be sure any neurobehavioral effects could not be attributed to lead.

When their children reached age 3, study mothers completed the Preschool Child Behavior Checklist, which assesses children鈥檚 behavior and emotions. The investigators found that women with higher fluoride exposure during pregnancy tended to rate their children higher for overall neurobehavioral problems.

The study team hopes their findings spur policymakers to create specific recommendations for fluoride consumption during pregnancy.

鈥淚 think this is important evidence, given that it鈥檚 the first U.S.-based study and findings are quite consistent with the other studies published in North America with comparable fluoride exposure levels,鈥� Malin said. 鈥淐onducting a nationwide U.S. study on this topic would be important, but I think the findings of the current study and recent studies from Canada and Mexico suggest that there is a real concern here.鈥�

Malin鈥檚 research is supported by the National Institute of Environmental 网红黑料 Sciences of the National Institutes of 网红黑料. The MADRES study is funded by the Environmental Protection Agency.