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This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common鈥�

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

2 Years - 25 Years

Sexes

All

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after鈥�

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

N/A - 22 Years

Sexes

All

The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin鈥�

Investigator

William Slayton

Status

Accepting Candidates

Ages

3 Years - 39 Years

Sexes

All