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This phase II trial tests the safety and best dose of revumenib in combination with chemotherapy, and evaluates whether this treatment improves the outcome in infants and young children who have leukemia that has come back (relapsed) or does not…

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

1 Month - 6 Years

Sexes

All

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open…

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

N/A - 50 Years

Sexes

All

This phase III trial compares the effects of nivolumab with chemo-immunotherapy versus chemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL). Immunotherapy with monoclonal antibodies, such as…

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

2 Years - N/A

Sexes

All