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Nikolaus McFarland, MD, PhD : Research

Neurologist

Photo of Nikolaus McFarland

Research at a glance

Top areas of exploration

  • Parkinson Disease , 43 publications
  • Supranuclear Palsy, Progressive , 18 publications
  • Multiple System Atrophy , 14 publications
  • Parkinsonian Disorders , 13 publications

Research activity

97 publications

4,899 citations

Why is this important?

Focus

Dr. McFarland is a member of the Norman Fixel Institute for Neurological Diseases and the Center for Translational Research in Neurodegenerative Disease (CTRND), which aims to bring the bench research closer to the bedside. His research focuses on understanding the pathological mechanisms of Parkinson disease and related disorders, and on identifying novel biomarkers for early detection and tracking of disease and therapeutic development. A primary goal of his research is to identify and to develop potential novel therapeutics for Parkinson disease and related disorders. His research extends also to the clinic where he is actively involved in multiple clinical trials for atypical Parkinson disorders and Huntington disease.

Active clinical trials

Enroll-HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America.…

Investigator
Nikolaus McFarland
Status
Accepting Candidates
Ages
18 Years - N/A
Sexes
All

My publications

97 publications

2019

Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis.

Laboratory investigation; a journal of technical methods and pathology

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2019

Neurite orientation dispersion and density imaging (NODDI) and free-water imaging in Parkinsonism.

Human brain mapping

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2019

Recognizing and treating atypical Parkinson disorders.

Handbook of clinical neurology

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2019

Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial.

The Lancet. Neurology

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2017

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease.

Neurology

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