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Nikolaus McFarland, MD, PhD : Research

Neurologist

Photo of Nikolaus McFarland

Research at a glance

Top areas of exploration

  • Parkinson Disease , 43 publications
  • Supranuclear Palsy, Progressive , 18 publications
  • Multiple System Atrophy , 14 publications
  • Parkinsonian Disorders , 13 publications

Research activity

97 publications

4,899 citations

Why is this important?

Focus

Dr. McFarland is a member of the Norman Fixel Institute for Neurological Diseases and the Center for Translational Research in Neurodegenerative Disease (CTRND), which aims to bring the bench research closer to the bedside. His research focuses on understanding the pathological mechanisms of Parkinson disease and related disorders, and on identifying novel biomarkers for early detection and tracking of disease and therapeutic development. A primary goal of his research is to identify and to develop potential novel therapeutics for Parkinson disease and related disorders. His research extends also to the clinic where he is actively involved in multiple clinical trials for atypical Parkinson disorders and Huntington disease.

Active clinical trials

ROCHE HD
Investigator
Nikolaus McFarland
Status
Accepting Candidates
Kinect-HD2

This is a Phase 3, open-label study to evaluate the long-term safety and tolerability of valbenazine, and to provide participants continued access to valbenazine for the treatment of chorea associated with Huntington disease.

Investigator
Nikolaus McFarland
Status
Accepting Candidates
Ages
18 Years - 75 Years
Sexes
All
PPMI Clinical -Establishing a Deeply Phenotyped PD Cohort (PPMI)

The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease…

Investigator
Nikolaus McFarland
Status
Accepting Candidates
Ages
30 Years - N/A
Sexes
All

My publications

97 publications

2014

Defining the clinically meaningful difference in gait speed in persons with Parkinson disease.

Journal of neurologic physical therapy : JNPT

•

2014

Driving errors in Parkinson's disease: moving closer to predicting on-road outcomes.

The American journal of occupational therapy : official publication of the American Occupational Therapy Association

•

2014

MRI reveals brain abnormalities in drug-naive Parkinson's disease.

Exercise and sport sciences reviews

•

2014

The "brittle response" to Parkinson's disease medications: characterization and response to deep brain stimulation.

PloS one

•

2014

The Exam Starts in the Hallway: Movement Disorders in Geriatric Psychiatry

The American Journal Of Geriatric Psychiatry