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Laura Jacobsen, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Laura Jacobsen

Research at a glance

Top areas of exploration

  • Diabetes Mellitus, Type 1 , 22 publications
  • Autoantibodies , 9 publications
  • C-Peptide , 8 publications
  • Insulin , 7 publications

Research activity

79 publications

1,927 citations

Why is this important?

Active clinical trials

TN-31 JAKPOT T1D

A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
Protocol TN-25

The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to…

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
8 Years - 45 Years
Sexes
All

My publications

79 publications

2020

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

Diabetes Care

2020

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening

Diabetologia

2019

Islet amyloidosis in a child with type 1 diabetes

Islets

2019

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

Pediatric Diabetes

2019

Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet’s Pathway to Prevention

Diabetes Care