2014
From anecdote to targeted therapy: the curious case of thalidomide in multiple myeloma.
Cancer cell
•Research at a glance
Top areas of exploration
- Transcription Factors , 58 publications
- DNA-Binding Proteins , 55 publications
- Gene Expression Regulation, Neoplastic , 38 publications
- Transcription, Genetic , 38 publications
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239 publications
2014
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
PLoS genetics
•2014
Molecular pathways: deregulation of histone h3 lysine 27 methylation in cancer-different paths, same destination.
Clinical cancer research : an official journal of the American Association for Cancer Research
•2014
Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies.
Leukemia
•2014
Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genes.
The Journal of biological chemistry
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