2020
Oncogenesis by E2A-PBX1 in ALL: RUNX and more
Blood
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- Transcription Factors , 58 publications
- DNA-Binding Proteins , 55 publications
- Gene Expression Regulation, Neoplastic , 38 publications
- Transcription, Genetic , 38 publications
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239 publications
2020
Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma.
Cancer letters
•2019
A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
Cancer Discovery
2019
An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia
Oncogene
2019
Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding
Journal of Biological Chemistry