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This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other…

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

3 Years - 29 Years

Sexes

All

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common…

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

2 Years - 25 Years

Sexes

All

This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care…

Investigator

Brian Stover

Status

Accepting Candidates

Ages

15 Years - 40 Years

Sexes

All